Steps of Development of R.B.C's, Development of red blood corpuscles

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Steps of Development of R.B.C's

Pro erythroblast is the first cell which is responsible for the formation of many red blood cells because when these cells formed ,divide several times and form many mature red blood cells.

The 1st generated cells are called besophil erythroblast because they can be stained with basic dyes. The at this time the cell has very little hemoglobin. However in succeeding generation the cell becomes filled approx 33% hemoglobin. At the same time the endoplasmic reticulum is reabsorbed. The cell at this steps is called reticul: eytes.

The remaining bchophilic materiel in reticnlocyte disappear with in 1--2 days and the cell is then converted into mature erythrocytes.

Development of red blood corpuscles

Areas of the body that produce Red cells

1. Embryonic Life:-

In early few weeks of Embryonic life, the primitive nucleated red blood cells are produced in the yolk sea.

Later on in the middle trimester of gestation red blood cells are produced by liver. Through reasonable no of R.B.C's are produced by the spleen and lymph nodes

2. After birth:-

The bone marrow is the main site of erythrogesis during the early year all bones are filled up with blood forming red marrow but by twentieth year almost all the long bones are replaced with inactive yellow and in this location. R.B.C formation stops only the upper ends of femur and humerus certain red marrow and continue to form red cells throughout the life.

In addition to this the vertebrae, the ribs and flat bones produce R.B.C's continuously.